Disclaimer
Products supplied by SYNA Labs Ltd are intended strictly for laboratory and scientific research purposes only. They are not medicines, are not approved for human or veterinary use, and must not be used to diagnose, treat, cure, or prevent any disease or medical condition. Products are not for human or animal consumption, cosmetic, food, or recreational use. By purchasing from SYNA Labs Ltd, customers confirm they are qualified individuals or entities purchasing solely for legitimate research purposes and agree to our Terms and Conditions and Research Use Policy.
MOTS-c is a synthetic analogue of a naturally occurring mitochondrial-derived peptide, encoded within mitochondrial rather than nuclear DNA. This distinctive origin has made it a focal point for laboratory research into mitochondrial biology, cellular signalling, and metabolic pathway regulation, particularly as a tool for studying communication between mitochondrial and nuclear regulatory systems.
In biochemical and cellular research settings, MOTS-c is used to investigate signalling mechanisms tied to cellular energy regulation, metabolic adaptation, stress-response pathways, and mitochondrial function more broadly. Researchers apply it to examine peptide-mediated cellular responses, transcriptional regulation, and intracellular signalling dynamics, with outcomes shaped by concentration, exposure duration, cell type, and overall study design.
Product: MOTS-c
Synonyms / Designations: MOTS-c, Mitochondrial Open Reading Frame of the 12S rRNA-c Peptide, MOTS-c Peptide
CAS Number: Not universally assigned across all research suppliers
Molecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂ (sequence-dependent reference value)
Molecular Weight: Approximately 2174.6 g/mol
Peptide Length: 16 Amino Acids
Peptide Type: Synthetic Mitochondrial-Derived Peptide
Purity: ≥99% (HPLC)
Appearance: White to off-white lyophilised powder
Pack Size: 10 mg
Storage: Desiccated, protected from light, stored at –20°C or below
Solubility: Soluble in water and buffered aqueous solutions.
Applications in Research
- Investigation of mitochondrial-derived peptide signalling pathways.
- Studies of cellular energy regulation and metabolic signalling.
- Analysis of mitochondrial-to-nuclear communication mechanisms.
- Evaluation of peptide-mediated stress-response pathways.
- Research involving cellular adaptation and intracellular signalling networks.
- Use as a reference compound in mitochondrial and metabolic biology studies.
Specifications Summary
| Parameter | Typical Value / Range |
| Purity (HPLC) | ≥99% |
| Peptide Type | Synthetic Mitochondrial-Derived Peptide |
| Peptide Length | 16 Amino Acids |
| Molecular Weight | Approximately 2174.6 g/mol |
| Appearance | White to off-white lyophilised powder |
| Solubility | Water and buffered aqueous solutions |
| Storage | –20 °C, desiccated, dark |
| Pack Size | 10mg |
Handling, Reconstitution & Stability
- Handle under dry conditions to minimise moisture absorption.
- Reconstitute using sterile water or an appropriate buffered aqueous solution according to experimental requirements.
- Avoid vigorous agitation during dissolution.
- Filter sterilize if needed (e.g. 0.22 µm) immediately prior to use.
- Aliquot and store reconstituted solutions at –20 °C (or lower) to avoid repeated freeze–thaw.
Precautions & Notes
- Experimental responses may vary according to concentration, exposure duration, and model system utilised; appropriate experimental controls are recommended when evaluating peptide-mediated cellular responses.
- Buffer composition, pH, and ionic strength may influence peptide stability and behaviour.
- Protect from prolonged exposure to moisture, light, and elevated temperatures.
- Experimental findings should be interpreted within the context of the specific assay conditions employed.
- MOTS-c is intended exclusively for laboratory research and analytical applications. For research use only — not for human consumption, therapeutic use, diagnostic procedures, performance enhancement, or veterinary applications.
