Disclaimer
Products supplied by SYNA Labs Ltd are intended strictly for laboratory and scientific research purposes only. They are not medicines, are not approved for human or veterinary use, and must not be used to diagnose, treat, cure, or prevent any disease or medical condition. Products are not for human or animal consumption, cosmetic, food, or recreational use. By purchasing from SYNA Labs Ltd, customers confirm they are qualified individuals or entities purchasing solely for legitimate research purposes and agree to our Terms and Conditions and Research Use Policy.
TB-500 is a synthetic research peptide derived from an active region of Thymosin Beta-4, a naturally occurring peptide involved in cellular signalling and cytoskeletal regulation. Its well-characterised structure and stability make it a valuable molecular tool for laboratory investigations into peptide-mediated cellular processes and intracellular signalling pathways.
In biochemical and cellular research settings, TB-500 is commonly utilised to study actin-binding interactions, cytoskeletal organisation, cellular migration dynamics, and peptide-regulated signalling mechanisms. Experimental outcomes may vary depending on concentration, exposure duration, assay conditions, and the model system employed, making TB-500 a widely used molecular tool for investigating cytoskeletal and peptide-mediated signalling in vitro and in vivo.
Product: TB-500
Synonyms / Designations: TB-500, Thymosin Beta-4 Fragment, Synthetic Thymosin β4 Analogue
CAS Number: Not universally assigned across all research suppliers
Molecular Formula: Sequence-dependent synthetic peptide
Molecular Weight: Approximately 4963.5 g/mol
Peptide Length: 43 Amino Acids
Purity: ≥99% (HPLC)
Appearance: White to off-white lyophilised powder
Pack Size: 5 mg
Storage: Desiccated, protected from light, stored at –20°C or below
Solubility: Soluble in water and buffered aqueous solutions.
Applications in Research
- Investigation of actin-regulatory and cytoskeletal signalling pathways.
- Studies of cellular migration and cell-matrix interaction dynamics.
- Evaluation of peptide-mediated intracellular signalling mechanisms.
- Analysis of cytoskeletal organisation and structural protein interactions.
- Research involving peptide-regulated cellular communication networks.
- Use as a reference compound in peptide and cell biology studies.
Specifications Summary
| Parameter | Typical Value / Range |
| Purity (HPLC) | ≥ 99% |
| Peptide Type | Synthetic Thymosin Beta-4 Analogue |
| Peptide Length | 43 Amino Acids |
| Appearance | White to off-white lyophilised powder |
| Molecular Weight | Approximately 4963.5 g/mol |
| Solubility | Water and buffered aqueous solutions |
| Storage | –20 °C, desiccated, dark |
| Pack Size | 5mg |
Handling, Reconstitution & Stability
- Handle under dry conditions to minimise moisture absorption.
- Reconstitute using sterile water or an appropriate buffered aqueous solution according to experimental requirements.
- Avoid vigorous agitation during dissolution.
- Filter sterilize if needed (e.g. 0.22 µm) immediately prior to use.
- Aliquot and store reconstituted solutions at –20 °C (or lower) to avoid repeated freeze–thaw.
Precautions & Notes
- Experimental performance may vary according to peptide concentration, exposure duration, and model system utilised; appropriate dose–response controls are recommended.
- Buffer composition, pH, and ionic strength may influence peptide stability and behaviour.
- Protect from prolonged exposure to moisture, light, and elevated temperatures.
- Experimental observations should be interpreted within the context of the specific assay system employed.
- TB-500 is intended exclusively for laboratory research and analytical applications. For research use only — not for human consumption, therapeutic use, diagnostic procedures, performance enhancement, or veterinary applications.
