Disclaimer
Products supplied by SYNA Labs Ltd are intended strictly for laboratory and scientific research purposes only. They are not medicines, are not approved for human or veterinary use, and must not be used to diagnose, treat, cure, or prevent any disease or medical condition. Products are not for human or animal consumption, cosmetic, food, or recreational use. By purchasing from SYNA Labs Ltd, customers confirm they are qualified individuals or entities purchasing solely for legitimate research purposes and agree to our Terms and Conditions and Research Use Policy.
NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme present in every living cell, central to cellular metabolism, energy transfer, and enzymatic regulation. As the oxidised form of the molecule, it functions as a key electron carrier across a wide range of cellular reactions, making it a foundational reagent in biochemical research.
In laboratory settings, NAD+ is used as a molecular tool for investigating redox biology, cellular metabolism, mitochondrial function, enzyme kinetics, and intracellular signalling. It acts as an essential cofactor for numerous enzymes, including dehydrogenases, ADP-ribosyltransferases, and sirtuin family proteins, and is applied across cellular, biochemical, and molecular biology studies examining metabolic regulation, energy homeostasis, and coenzyme-dependent signalling under controlled conditions.
Product: NAD+
Synonyms / Designations: Nicotinamide Adenine Dinucleotide (Oxidised Form), NAD+, β-Nicotinamide Adenine Dinucleotide
CAS Number: 53-84-9
Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
Molecular Weight: 663.43 g/mol
Compound Type: Coenzyme / Nucleotide Cofactor
Purity: ≥99% (HPLC)
Appearance: White to off-white lyophilised powder
Pack Size: 500 mg
Storage: Desiccated, protected from light, stored at –20°C or below
Solubility: Freely soluble in water and aqueous buffer systems.
Applications in Research
- Investigation of cellular metabolism and bioenergetics.
- Studies of mitochondrial function and redox regulation.
- Evaluation of NAD+-dependent enzyme activity.
- Research involving sirtuin-mediated signalling pathways.
- Analysis of intracellular energy transfer mechanisms.
- Enzyme kinetics and cofactor-dependent biochemical assays.
- Cell culture and molecular biology applications.
Specifications Summary
| Parameter | Typical Value / Range |
| Purity (HPLC) | ≥99% |
| Compound Type | Coenzyme / Nucleotide Cofactor |
| Molecular Formula | C₂₁H₂₇N₇O₁₄P₂ |
| Molecular Weight | 663.43 g/mol |
| Appearance | White to off-white lyophilised powder |
| Solubility | Freely soluble in water and aqueous buffers |
| Storage | –20 °C, desiccated, dark |
| Pack Size | 500mg |
Handling, Reconstitution & Stability
- Handle under dry conditions to minimise moisture exposure.
- Reconstitute using sterile water or an appropriate aqueous buffer according to experimental requirements.
- Avoid prolonged exposure to ambient temperatures during preparation.
- Prepare fresh solutions where possible for optimal stability.
- Aliquot reconstituted solutions prior to storage and protect from prolonged light exposure.
- Store reconstituted solutions at –20 °C (or lower) to avoid repeated freeze–thaw.
Precautions & Notes
- Experimental performance may vary depending on concentration, pH, temperature, and assay conditions; appropriate controls should be used when conducting cofactor-dependent experiments.
- NAD+ is sensitive to degradation under unsuitable storage conditions.
- Buffer composition and ionic strength may influence stability and activity in certain applications.
- Protect from excessive heat, moisture, and prolonged light exposure.
- NAD+ is intended exclusively for laboratory research and analytical applications. For research use only — not for human consumption, therapeutic use, diagnostic procedures, performance enhancement, or veterinary applications.
